Our Technology

ProAxsis Has Developed a Range of Unique Molecules, known as ProteaseTags ®


Proteases are a large grouping of biological molecules that play pivotal regulatory roles in most physiological processes required for life.

Unregulated protease activity (which occurs when the normal control of their action is lost) can be a trigger of many important human diseases thereby making active proteases important.

Therapeutic Targets and Biomarkers of Disease Activity

Standard methods of detection and quantification of active proteases are based on the hydrolysis of chromogenic or fluorogenic peptide substrates. Biological samples contain multiple activities with the potential to hydrolyse these substrates and are not sufficiently selective for biomarker studies.

Typical antibody-based systems e.g. ELISA (Enzyme-linked ImmunoSorbent Assay) will only detect total protein with no indication of the fraction associated with the active form of the enzyme.
health care researchers working in life science laboratory medical science e1621147225728
microscopes for researchers in medical laboratories e1621147243234

ProteaseTag ® Technology

ProAxsis has developed a range of unique molecules, known as ProteaseTags ®, which have the capacity to rapidly and selectively bind active proteases, including those which are biomarkers of diagnostic and prognostic value.

ProteaseTags ® rapidly provide a visual readout of active proteases in complex biological samples with a high level of specificity and selectivity. In diseases characterised by abnormal protease action including but not limited to COPD, Bronchiectasis and Cystic Fibrosis. ProteaseTag ® test systems have the potential to be incorporated into Point of Care tests, Companion Diagnostics, and activity-based immunoassays.

Chemical Research

Lorem ipsum dolor sit amet consectetur adipiscing.

Pathologycam Testing

Lorem ipsum dolor sit amet consectetur adipiscing.

Forensic Science

Lorem ipsum dolor sit amet consectetur adipiscing.

Asset 2 ATS4M76

How It Works ?

Duis condimentum nunc metus, maximus porta velit temporin. 

Key Benefits

ProteaseTags ® may be used as tools to detect and quantify the activity of a single protease species within a complex biological sample.

Lorem ipsum dolor sit amet, consectetuer adipiscing elit. Aenean commodo ligula eget dolor. Aenean massaum sociis natoque penatibus.