News

ProAxsis CSO to present at global plasminogen conference

Date : February 12, 2016

BrianWalker

Professor Brian Walker, the Chief Scientific Officer of ProAxsis, will be presenting an abstract at the Gordon Research Conference - Plasminogen Activation and Extracellular Proteolysis, taking place in Ventura, California.  The abstract is entitled “The development of Protease-Tags for plasmin”, and will be presented on February 16th, 2016.

Professor Walker said: “Plasmin, a serine protease product of plasminogen activation, in addition to playing a key role in the fibrinolytic system, exerts a broad spectrum of effects on key physiological/pathological processes. For example, aberrant plasmin activity is thought to be implicated in the formation of fibrotic lesions observed in Acute Lung Injury, in the development of preeclampsia, and in modulating bacterial infection and virulence. As part of our on-going development of assays for the selective and precise measurement of active serine proteases, we have developed a range of Protease-Tags of plasmin. When incorporated into our proprietary Activity Immunoassay Platform, this permits the precise quantification of plasmin and should prove effective in measuring exclusively levels of the active protease in biological and clinical samples, even in the presence of other closely related serine proteases.

ProAxsis is part of the NetScientific group and is one of the group’s core portfolio companies.  The company is also supported by QUBIS, the commercialisation arm of Queens University.